RCC Sections Loss and Orbiter Breakup TimeLine
The annotated timeline below assumes that the damage to Shuttle Columbia was caused by an icy stalactite from the External Tank shattering an inboard (#6 or #7) RCC left wing leading-edge section on launch. It further assumes that the object seen by radar to detach in orbit (after a mild manoeuvre) and float in the Shuttle's vicinity was a large segment of that shattered RCC section (having become dislodged after a number of "towards and away from sun" in-orbit heat-cycle exposures). Based upon the fact that the RCC section's anti-oxidizer coating would have been compromised by the shattering, it is theorized that re-entry heating would have quickly caused the remaining segments of that shattered RCC section to dislodge and create a superheated (S/H) plasma spike ahead of that section (due to the oblique flat-plate of the now uncovered aluminium wing leading-edge flying at a very high Mach No). In seq 24.8 below, the increase in temperature rise-rate of the supply water nozzle (21ft ahead of the RCC sections) is explained by the flat-plate effect  generating the "projected ahead" super-heated plasma spike - and that plasma spike being initially deflected inwards towards the nose of the Orbiter by the (then) intact RCC section just outboard of the initially shattered section.

The progressive "unzippering" of further outboard RCC sections would have eventually led to a loss of lateral control (and a change in shape and ahead projection of the S/H plasma spike). Contributing to this would have been the breach burnt between the flat aluminium wing leading-edge and the wheel-well (just behind it). It has been established that the wheel-well was "eaten out" from the inside and a through pathway (an exit) latterly established for itself by the superheated plasma. The New Mexico USAF Starfire photo (seq 49.55) later captured the ahead-projected super-heated plasma spike on film. It is possible (seq 71/72) that the left wheel-well door opened, contributing to the unmanageable asymmetric drag rise and causing the loss of control seconds later.

The evidence for this process starts at seq 24.8 (time 1352:52) below (and is explained further in this link). Some supporting links are shown at the bottom of this timeline.

Seq Time Event Observation/Deduction
14 1344:09 Entry Interface  
20 1349:32 Initial Roll starts exposing LE to varying angles of attack (which may start dislodging residual shattered RCC section, particularly as section heats up (anti-oxidization seal no longer intact))
20.5 1350.30 first re-entry heating  
21 1350:53 start of peak heating  
21.5 1351:19 earliest off-nominal events (continue for 90 secs) roll & yaw thruster firings (so surface damage requiring compensation must have existed already)
24 1352:17 left gear brake-line D starts heating up located wheel-well inbd sidewall (possibly indicates that superheated plasma is heat-transferring by conduction even if wheel-well is not yet penetrated via L.E. breach).
24.3 1352:25 off-nominal comms dropouts first experienced at 1350.00. Upper Left antenna (S-Band signal shielded by superheated plasma projection ahead of left wing). Subsequent drop-outs likely also caused by plasma and changing aspect to receiver station.
24.8 1352:52 Supply H2O dump Nozzle temps A/B show temporary increase in temp rise- rate (15 second duration of high rise rate). 24 secs later returns normal Unfortunately no indication of any assoc normal re-entry roll manoeuvring that may have increased AoA and projected S/H plasma bubble further ahead of leading edge (Supply H2O dump nozzle is about 21feet ahead of the RCC tiled leading edge).
26 1352:41 left gear brake-lines A&C begin off nominal temp-rise further conduction of S/H plasma heat into the (as yet) unbreached wheel-well (due to heat having reached aluminium wing structure at the L.E.)
26.6 1352:47 Supply H2O dump Nozzle temps A/B return to normal rise-rate S/H plasma bubble [due to flat plate effect of single missing RCC section] now no longer projecting as far ahead of leading edge -nor being deflected inboard toward Orbiter nose by next RCC section along - due to progressive lateral erosion of that [next along] RCC section (and its eventual disappearance), plus gradually reducing Mach No generating slightly smaller shocks. Timing of Vacuum vent (further aft than dump nozzle) reflects rate of S/H plasma bubble's retreat back towards leading edge. In addition events from this point forward would indicate that LE breach has reached the wheel-well (a further cause for S/H plasma bubble no longer being projected as far forward and inboard).
26.65 1352.55 Vacuum vent temp returns to typical rise rate.
26.7 1352:56-59 Left INBD Elevon Lower Skin Temp - OSL Because aileron is down-deflected to counter L rolling tendency it is receiving aerodynamic cooling (that counters the surface heating)
29.5 1353:26 coast crossing any initial RCC section fragment separation overwater may not have been noted by ships at sea.
30.3 1353:54 indications of off-nominal heat-rise in lower mid-fuselage areas abnormal S/H plasma heating has transferred by conduction along wing structure and structural members and reaches the fuselage.
32.1 1353:44 -50 visual debris in night sky Simultaneous events. Probability of wing LE  to wheel-well plasma channel established at this point (as RCC sections continue to erode away outboard)
32.5 1353:46 Left gear brake line temp A starts rapid heat-rise
32.7 1353:54-58 Momentary brightening of plasma trail possibly caused by a new material being incendiarized as S/H plasma reached the wheel-well. It may also have been the moment that a wheel-well plasma exit hole was established (entry/exit of plasma into wheel-well likely to have been near coincidental). However, unlikely due next event (seq 33) and event at 1354:33 (seq 36.5)
33 1354:10 LMG brake-line temp B abnormal temp-rise caused not by conduction (or direct flow impingement) but by convection of plasma circulating within wheel-well (over the preceding 24 secs).
34 1354:20 start of slow aileron trim change force-trim (holding LIE/LOE down) changes due to increasing drag of gradually "eating away" (towards outboard) of LE RCC sections and plasma bubble shape-change
35 1354:22 rapid increase in temp rise-rate along mid-fuselage bond-line (& aft fuse BL) rapid heat-rise within the now-penetrated wheel well is being conducted along structural members to the mid-fuselage (and very shortly thereafter to the aft Left fuselage sidewall)
36.5 1354:33.3 to

1354:33.9

Flash #1 - Orbiter envelope suddenly brightened (duration 0.3 sec), leaving noticeably luminescent signature in plasma trail (Debris #6 -very bright) Although RCS jets fired at this time also, their intervention was possibly due to the wheelwell S/H plasma exit hole becoming established (initial pinhole widening). Nature of exiting plasma changed by journey through wheel-well
36.6 1354:35-37 Debris #6 - Very bright debris seen leaving the Orbiter incendiarized debris from wheel-well exiting the widened exit-hole
40.1 1355:21-27 Debris #8 - Eighth report of debris observed leaving the Orbiter. Event was followed by momentary brightening of plasma trail. Debris event #'s reached #15 by 1356:13. Likely attributable to further RCC sections being lost plus some under-wing tiles.
42.8 1355:58 Debris $14 Debris #6 and #14 were the two brightest events
49.55 1357:19-29 Starfire Photo over New Mexico shows S/H plasma bubble prominently projecting forward of inboard left wing and a stream of particles aft of inboard wing section.
49.6 1357:19-24 L MLG tyres show pressure changes increases due to wheel-well heat throughflow?
54 1358:03 Start of "sharp" aileron trim increase preceded at 1358:00:48/01:44 by a 0.96sec RCS pulse firing (i.e. then computer decided that asymm situation was permanent and required a trim-change)
55.5 1358:20 crossing New Mexico/Texas border

209,800ft and Mach 19.5

 
57/58 1358:32 both tyre pressures trending down simultaneously pierced(?) or thermal fuses have operated (more likely)
58.5 1358:32 wheel temp trending down towards OSL sensors are being knocked out by high wheel-well temps
60/64 1358:38-40 both L tyres' pressures OSL tyres' thermal fuses have operated (seqs 57/58)
70 1359:06 Left gear downlock indication microswitch (or wiring) cooked by high temperatures (gear uplock still indicating)
  1359:07 aileron trim reached max allowable by FCS as a result of RCC section loss and resulting wing tile losses
71/72 1359:30 Both R2R and R3R RCS jets firing long pulses (each) of 5 secs at least (indicating massive rise in drag asymmetry) - suggest wheel-well door had opened- initiating LOC (loss of control)
73 1359:31 significant elevon deflections Left: -8.11 deg (up); Right: -1.15 deg (up) (together with RCS firings insufficient to compensate wheel-well door opening)
  1359:32 loss of signal LOS attributable to rapidly changing Orbiter flight attitudes. BREAKUP delayed until loss of control had been in effect for period of approx 50 secs. Some indications that flight control system's force-fighting in that period was due to interdiction of wiring by wheel-well events plus voltage drops caused by massive shorting..
100 1400:02-06 large debris seen falling from Orbiter Pre-Break-up LOC apparently initiated by wheel-well door opening (and not left wing burn-though)
110 1400:21-25 Main Vehicle Body Orbiter Breakup  

LINKS

An Annotated Shuttle TimeLine and a New Theory Columbia inquiry looks closely at damage to leading edge
Shuttle Left Wing Cutaway Diagrams (s/m/L) NASA Pondering Changes to the Shuttle
The Flat-Plate Effect Creates Superheated Plasma Experts Blame Hole in Leading Edge for Heat Buildup
The Projection forward of the left Wing L.E. (Starfire Photo) An Analysis of the Shutle's Last Seconds

The Explanation of why it may have been an RCC failure

The Sacrificial Leading-Edge Wedge (protecting the RCC)
USAF Imagery Confirms Columbia Wing Damaged Genesis of a Failure
The RCC Story within a Story Why Super-Heated Plasma?
Characteristics of the Leading Edge RCC Sections Pprune thread on Shuttle Columbia

Click image (above) for larger image (on a new page)- .68mb download

A One Meg Download Tribute to the Columbia Crew (Speakers on) in Power Point Screenshow format

LINK